2020 |
| Title |
Authors |
Journal |
| Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. |
Li X
Lin X |
Nature genetics |
| Genetic Determinants of Electrocardiographic P-wave Duration and Relation to Atrial Fibrillation. |
Weng LC
Lubitz SA |
Circulation. Genomic and precision medicine |
| Mitochondrial DNA copy number and diabetes: the Atherosclerosis Risk in Communities (ARIC) study. |
DeBarmore B
Young JH |
BMJ open diabetes research & care |
| Multi-Ethnic Genome-Wide Association Study of Decomposed Cardioelectric Phenotypes Illustrates Strategies to Identify and Characterize Evidence of Shared Genetic Effects for Complex Traits. |
Baldassari AR
Avery CL |
Circulation. Genomic and precision medicine |
| Analysis of putative cis-regulatory elements regulating blood pressure variation. |
Nandakumar P
Chakravarti A |
Human molecular genetics |
| Thinking outside the nucleus: Mitochondrial DNA copy number in health and disease. |
Castellani CA
Arking DE |
Mitochondrion |
| Mitochondrial DNA Copy Number and Incident Heart Failure: The Atherosclerosis Risk in Communities (ARIC) Study. |
Hong YS
Guallar E |
Circulation |
| Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction. |
Ntalla I
Munroe PB |
Nature communications |
| Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. |
de Las Fuentes L
Fornage M |
Molecular psychiatry |
| Consistent RNA sequencing contamination in GTEx and other data sets. |
Nieuwenhuis TO
Halushka MK |
Nature communications |
| Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. |
Zekavat SM
Natarajan P |
Nature communications |
| High-Risk, High-Reward Genetics in ASD. |
Castellani CA
Arking DE |
Neuron |
| De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population. |
Kessler MD
O'Connor TD |
Proceedings of the National Academy of Sciences of the United States of America |
| Evaluation of mitochondrial DNA copy number estimation techniques. |
Longchamps RJ
Arking DE |
PloS one |
2019 |
| Title |
Authors |
Journal |
| Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders. |
Consortium |
Cell |
| Effect of Sex and Underlying Disease on the Genetic Association of QT Interval and Sudden Cardiac Death. |
Mitchell RN
Arking DE |
Journal of the American Heart Association |
| Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma. |
Kachroo P
Lasky-Su JA |
Chest |
| Human cardiac myosin light chain 4 (MYL4) mosaic expression patterns vary by sex. |
Wang TY
Halushka MK |
Scientific reports |
| New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders. |
Evangelou E
Elliott P |
Nature human behaviour |
| Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA Transcription Factor Binding and Disrupts Conduction System Development and Function. |
Vincentz JW
Firulli AB |
Circulation research |
| A meta-analysis of genome-wide association studies identifies multiple longevity genes. |
Deelen J
Murabito JM |
Nature communications |
| Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways. |
Lam M
Lencz T |
American journal of human genetics |
| Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. |
de Vries PS
Morrison AC |
American journal of epidemiology |
| Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits. |
van Setten J
Isaacs A |
European journal of human genetics : EJHG |
| Multiple SCN5A variant enhancers modulate its cardiac gene expression and the QT interval. |
Kapoor A
Chakravarti A |
Proceedings of the National Academy of Sciences of the United States of America |
| Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. |
Davies G
Deary IJ |
Nature communications |
| A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. |
Sung YJ
Morrison AC |
Human molecular genetics |
| Association Between HIV Infection and Mitochondrial DNA Copy Number in Peripheral Blood: A Population-Based, Prospective Cohort Study. |
Sun J
Kirk GD |
The Journal of infectious diseases |
| NT -pro BNP as a Mediator of the Racial Difference in Incident Atrial Fibrillation and Heart Failure. |
Whitman IR
Marcus GM |
Journal of the American Heart Association |
| Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample. |
Petty LE
Below JE |
Human molecular genetics |
| Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. |
Bentley AR
Cupples LA |
Nature genetics |
| Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation: A Mendelian Randomization Study. |
Ellervik C
Chasman DI |
JAMA cardiology |
| Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits. |
Kraja AT
North KE |
American journal of human genetics |
2018 |
| Title |
Authors |
Journal |
| Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation. |
Choi SH
Ellinor PT |
JAMA |
| Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. |
Evangelou E
Caulfield MJ |
Nature genetics |
| A comprehensive evaluation of the genetic architecture of sudden cardiac arrest. |
Ashar FN
Sotoodehnia N |
European heart journal |
| Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation. |
Teumer A
Medici M |
Nature communications |
| Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. |
Evangelou E
Caulfield MJ |
Nature genetics |
| Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018). |
Lam M
Lencz T |
Twin research and human genetics : the official journal of the International Society for Twin Studies |
| Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. |
Zekavat SM
Natarajan P |
Nature communications |
| Deep-coverage whole genome sequences and blood lipids among 16,324 individuals. |
Natarajan P
Kathiresan S |
Nature communications |
| PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. |
van Setten J
Sotoodehnia N |
Nature communications |
| Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6. |
Prins BP
Jamshidi Y |
Genome biology |
| Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. |
Zekavat SM
Natarajan P |
Nature communications |
| Serum 6-Bromotryptophan Levels Identified as a Risk Factor for CKD Progression. |
Tin A
Grams ME |
Journal of the American Society of Nephrology : JASN |
| Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. |
Savage JE
Posthuma D |
Nature genetics |
| Analysis of shared heritability in common disorders of the brain. |
Anttila V
Murray R |
Science (New York, N.Y.) |
| Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. |
Feitosa MF
Levy D |
PloS one |
| Multi-ethnic genome-wide association study for atrial fibrillation. |
Roselli C
Ellinor PT |
Nature genetics |
| Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. |
Davies G
Deary IJ |
Nature communications |
| Common Coding Variants in SCN10A Are Associated With the Nav1.8 Late Current and Cardiac Conduction. |
Macri V
Ellinor PT |
Circulation. Genomic and precision medicine |
| Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval. |
Lin H
Isaacs A |
Circulation. Genomic and precision medicine |
| Genome-Wide Associations of Global Electrical Heterogeneity ECG Phenotype: The ARIC (Atherosclerosis Risk in Communities) Study and CHS (Cardiovascular Health Study). |
Tereshchenko LG
Arking DE |
Journal of the American Heart Association |
| Transethnic Evaluation Identifies Low-Frequency Loci Associated With 25-Hydroxyvitamin D Concentrations. |
Hong J
Billings LK |
The Journal of clinical endocrinology and metabolism |
| A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. |
Sung YJ
Chasman DI |
American journal of human genetics |
| CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis. |
Guo L
Finn AV |
The Journal of clinical investigation |
| Stress-Dependent Association Between Polygenic Risk for Schizophrenia and Schizotypal Traits in Young Army Recruits. |
Hatzimanolis A
Stefanis NC |
Schizophrenia bulletin |
| Whole genome sequence analyses of brain imaging measures in the Framingham Study. |
Sarnowski C
Seshadri S |
Neurology |
| Cardiomyocytes have mosaic patterns of protein expression. |
Wang TY
Halushka MK |
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology |
| ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals. |
Bihlmeyer NA
Sotoodehnia N |
Circulation. Genomic and precision medicine |
2017 |
| Title |
Authors |
Journal |
| Association between mitochondrial DNA copy number and sudden cardiac death: findings from the Atherosclerosis Risk in Communities study (ARIC). |
Zhang Y
Arking DE |
European heart journal |
| Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets. |
Lam M
Lencz T |
Cell reports |
| The Loss of GSTM1 Associates with Kidney Failure and Heart Failure. |
Tin A
Grams ME |
Journal of the American Society of Nephrology : JASN |
| Association of Mitochondrial DNA Copy Number With Cardiovascular Disease. |
Ashar FN
Arking DE |
JAMA cardiology |
| GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium. |
Trampush JW
Lencz T |
Molecular psychiatry |
| Cross-tissue integration of genetic and epigenetic data offers insight into autism spectrum disorder. |
Andrews SV
Fallin MD |
Nature communications |
| Toward the human cellular microRNAome. |
McCall MN
Halushka MK |
Genome research |
| Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium. |
Weng LC
Lubitz SA |
Scientific reports |
| Moderate Coffee Intake Can Be Part of a Healthy Diet. |
Guallar E
Zhao D |
Annals of internal medicine |
| Circulating ceruloplasmin, ceruloplasmin-associated genes, and the incidence of atrial fibrillation in the atherosclerosis risk in communities study. |
Arenas de Larriva AP
Alonso A |
International journal of cardiology |
| Genome-wide association study to identify variants associated with acute severe vaso-occlusive pain in sickle cell anemia. |
Chaturvedi S
DeBaun MR |
Blood |
| Fifteen Genetic Loci Associated With the Electrocardiographic P Wave. |
Christophersen IE
Ellinor PT |
Circulation. Cardiovascular genetics |
| Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. |
Wain LV
Ehret GB |
Hypertension (Dallas, Tex. : 1979) |
| Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders. |
Weiner DJ
Robinson EB |
Nature genetics |
| Discovery of novel heart rate-associated loci using the Exome Chip. |
van den Berg ME
Munroe PB |
Human molecular genetics |
| Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. |
Christophersen IE
Ellinor PT |
Nature genetics |
| Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia. |
Consortium |
Molecular autism |
| Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study. |
Haycock PC
Davey Smith G |
JAMA oncology |
| SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. |
Li M
Chu AY |
Journal of the American Society of Nephrology : JASN |
| GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium. |
Trampush JW
Lencz T |
Molecular psychiatry |
| Genetic Obesity and the Risk of Atrial Fibrillation: Causal Estimates from Mendelian Randomization. |
Chatterjee NA
Albert CM |
Circulation |
| Exaggerated CpH methylation in the autism-affected brain. |
Ellis SE
Arking DE |
Molecular autism |
| Usefulness of Maintaining a Normal Electrocardiogram Over Time for Predicting Cardiovascular Health. |
Soliman EZ
Alonso A |
The American journal of cardiology |
2016 |
| Title |
Authors |
Journal |
| Gene-gene Interaction Analyses for Atrial Fibrillation. |
Lin H
Ellinor PT |
Scientific reports |
| GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium. |
Matteini AM
Murabito JM |
Aging cell |
| Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans. |
Evans DS
Sotoodehnia N |
Human molecular genetics |
| The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. |
Ehret GB
Munroe PB |
Nature genetics |
| 52 Genetic Loci Influencing Myocardial Mass. |
van der Harst P
de Bakker PIW |
Journal of the American College of Cardiology |
| Whole Exome Sequencing in Atrial Fibrillation. |
Lubitz SA
Lin H |
PLoS genetics |
| Association between Mitochondrial DNA Copy Number in Peripheral Blood and Incident CKD in the Atherosclerosis Risk in Communities Study. |
Tin A
Arking DE |
Journal of the American Society of Nephrology : JASN |
| Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. |
van Leeuwen EM
van Duijn CM |
Journal of medical genetics |
| Genetic Investigation Into the Differential Risk of Atrial Fibrillation Among Black and White Individuals. |
Roberts JD
Marcus GM |
JAMA cardiology |
| Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study. |
Prins BP
Alizadeh BZ |
PLoS medicine |
| Rare coding TTN variants are associated with electrocardiographic QT interval in the general population. |
Kapoor A
Chakravarti A |
Scientific reports |
| Transcriptome analysis of cortical tissue reveals shared sets of downregulated genes in autism and schizophrenia. |
Ellis SE
Arking DE |
Translational psychiatry |
| Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram. |
Verweij N
Van Der Harst P |
Human molecular genetics |
| Impact of genetic variants on the upstream efficacy of renin-angiotensin system inhibitors for the prevention of atrial fibrillation. |
Roberts JD
Marcus GM |
American heart journal |
| Association of Lipid-Related Genetic Variants with the Incidence of Atrial Fibrillation: The AFGen Consortium. |
Norby FL
Alonso A |
PloS one |
| Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. |
Pattaro C
Fox CS |
Nature communications |
2015 |
| Title |
Authors |
Journal |
| Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C. |
van Leeuwen EM
van Duijn C |
NPJ aging and mechanisms of disease |
| Editorial overview: Molecular and genetic bases of disease: Enter the post-GWAS era. |
Arking D
Rommens J |
Current opinion in genetics & development |
| Common genetic variation and schizophrenia polygenic risk influence neurocognitive performance in young adulthood. |
Hatzimanolis A
Avramopoulos D |
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics |
| Genetic studies of body mass index yield new insights for obesity biology. |
Locke AE
Speliotes EK |
Nature |
| New genetic loci link adipose and insulin biology to body fat distribution. |
Shungin D
Mohlke KL |
Nature |
| Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. |
Maier R
Lee SH |
American journal of human genetics |
| Association of mitochondrial DNA levels with frailty and all-cause mortality. |
Ashar FN
Arking DE |
Journal of molecular medicine (Berlin, Germany) |
| Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. |
Consortium |
Nature neuroscience |
| Beat-to-beat spatiotemporal variability in the T vector is associated with sudden cardiac death in participants without left ventricular hypertrophy: the Atherosclerosis Risk in Communities (ARIC) Study. |
Waks JW
Tereshchenko LG |
Journal of the American Heart Association |
2014 |
| Title |
Authors |
Journal |
| Genetic diversity is a predictor of mortality in humans. |
Bihlmeyer NA
Arking DE |
BMC genetics |
| Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism. |
Gupta S
Arking DE |
Nature communications |
| Electrocardiographic deep terminal negativity of the P wave in V(1) and risk of sudden cardiac death: the Atherosclerosis Risk in Communities (ARIC) study. |
Tereshchenko LG
Soliman EZ |
Journal of the American Heart Association |
| Risk factors for atrial fibrillation in patients with normal versus dilated left atrium (from the Atherosclerosis Risk in Communities Study). |
Qureshi W
Herrington D |
The American journal of cardiology |
| A common SCN5A variant is associated with PR interval and atrial fibrillation among African Americans. |
Ilkhanoff L
Sotoodehnia N |
Journal of cardiovascular electrophysiology |
| Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. |
Arking DE
Newton-Cheh C |
Nature genetics |
| Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index. |
Hoggart CJ
Kutalik Z |
PLoS genetics |
| An enhancer polymorphism at the cardiomyocyte intercalated disc protein NOS1AP locus is a major regulator of the QT interval. |
Kapoor A
Chakravarti A |
American journal of human genetics |
| Sequencing of SCN5A identifies rare and common variants associated with cardiac conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. |
Magnani JW
Sotoodehnia N |
Circulation. Cardiovascular genetics |
| Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese. |
Lubitz SA
Ellinor PT |
Journal of the American College of Cardiology |
| Common variation in fatty acid metabolic genes and risk of incident sudden cardiac arrest. |
Lemaitre RN
Siscovick DS |
Heart rhythm |
| Targeted sequencing in candidate genes for atrial fibrillation: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study. |
Lin H
Benjamin EJ |
Heart rhythm |
| Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval. |
Avery CL
Psaty BM |
The pharmacogenomics journal |
| Novel gene variants predict serum levels of the cytokines IL-18 and IL-1ra in older adults. |
Matteini AM
Walston JD |
Cytokine |
2013 |
| Title |
Authors |
Journal |
| RNA-Seq optimization with eQTL gold standards. |
Ellis SE
Arking DE |
BMC genomics |
| Defining the contribution of CNTNAP2 to autism susceptibility. |
Sampath S
Chakravarti A |
PloS one |
| SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs). |
Abrahams BS
Packer A |
Molecular autism |
| The QT interval and risk of incident atrial fibrillation. |
Mandyam MC
Marcus GM |
Heart rhythm |
| Association between baseline fetal hemoglobin levels and incidence of severe vaso-occlusive pain episodes in children with sickle cell anemia. |
Bhatnagar P
Debaun MR |
Pediatric blood & cancer |
| Genome-wide meta-analysis of systolic blood pressure in children with sickle cell disease. |
Bhatnagar P
Arking DE |
PloS one |
| Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. |
Lee SH
Wray NR |
Nature genetics |
| Fast association tests for genes with FAST. |
Chanda P
Bader JS |
PloS one |
| A Novel Stratification Method in Linkage Studies to Address Inter- and Intra-Family Heterogeneity in Autism. |
Talebizadeh Z
Hu VW |
PloS one |
| Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. |
den Hoed M
Loos RJ |
Nature genetics |
| Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: a genome-wide association study of 13,372 participants. |
Deo R
Whitsel EA |
Heart rhythm |
| Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. |
O'Seaghdha CM
Bochud M |
PLoS genetics |
2012 |
| Title |
Authors |
Journal |
| Impact of ancestry and common genetic variants on QT interval in African Americans. |
Smith JG
Newton-Cheh C |
Circulation. Cardiovascular genetics |
| Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts. |
Butler AM
Avery CL |
Circulation. Cardiovascular genetics |
| Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans. |
Bae HT
Steinberg MH |
Blood |
| Genetic variants in platelet factor 4 modulate inflammatory and platelet activation biomarkers. |
Bhatnagar P
Fletcher CA |
Circulation. Cardiovascular genetics |
| Validated SNPs for eGFR and their associations with albuminuria. |
Ellis JW
O'Seaghdha CM |
Human molecular genetics |
| Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. |
Okada Y
Tanaka T |
Nature genetics |
| Comprehensive evaluation of imputation performance in African Americans. |
Chanda P
Arking DE |
Journal of human genetics |
| No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels. |
Scott RA
Langenberg C |
Diabetes |
| Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. |
Perry JR
Cauchi S |
PLoS genetics |
| Meta-analysis identifies six new susceptibility loci for atrial fibrillation. |
Ellinor PT
Kääb S |
Nature genetics |
| Postmortem cardiac tissue maintains gene expression profile even after late harvesting. |
Gupta S
Arking DE |
BMC genomics |
| The genetics of sudden cardiac death. |
Arking DE
Sotoodehnia N |
Annual review of genomics and human genetics |
| Fine-mapping and initial characterization of QT interval loci in African Americans. |
Avery CL
North KE |
PLoS genetics |
| A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia. |
Milton JN
Klings ES |
PloS one |
2011 |
| Title |
Authors |
Journal |
| The association of genetic variants in interleukin-1 genes with cognition: findings from the cardiovascular health study. |
Benke KS
Fallin MD |
Experimental gerontology |
| Disruption of p16 and activation of Kras in pancreas increase ductal adenocarcinoma formation and metastasis in vivo. |
Qiu W
Su GH |
Oncotarget |
| Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. |
Chambers JC
Kooner JS |
Nature genetics |
| Large-scale candidate gene analysis in whites and African Americans identifies IL6R polymorphism in relation to atrial fibrillation: the National Heart, Lung, and Blood Institute's Candidate Gene Association Resource (CARe) project. |
Schnabel RB
Heckbert SR |
Circulation. Cardiovascular genetics |
| Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. |
Ehret GB
Johnson T |
Nature |
| Exploring biologically relevant pathways in frailty. |
Ho YY
Walston J |
The journals of gerontology. Series A, Biological sciences and medical sciences |
| Gene-based tests of association. |
Huang H
Arking DE |
PLoS genetics |
| Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. |
Fox ER
Levy D |
Human molecular genetics |
| Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals. |
Arking DE
Chugh SS |
PLoS genetics |
| Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients. |
Bhatnagar P
Keefer JR |
Journal of human genetics |
| CUBN is a gene locus for albuminuria. |
Böger CA
Kao WH |
Journal of the American Society of Nephrology : JASN |
| A common connexin-40 gene promoter variant affects connexin-40 expression in human atria and is associated with atrial fibrillation. |
Wirka RC
Smith JD |
Circulation. Arrhythmia and electrophysiology |
2010 |
| Title |
Authors |
Journal |
| Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. |
Yang Q
Coresh J |
Circulation. Cardiovascular genetics |
| Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. |
Soranzo N
Meigs JB |
Diabetes |
| Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. |
Sotoodehnia N
Arking DE |
Nature genetics |
| Genome-wide association analysis identifies multiple loci related to resting heart rate. |
Eijgelsheim M
O'Donnell CJ |
Human molecular genetics |
| Independent susceptibility markers for atrial fibrillation on chromosome 4q25. |
Lubitz SA
Ellinor PT |
Circulation |
| Parent-of-origin effects in autism identified through genome-wide linkage analysis of 16,000 SNPs. |
Fradin D
Fallin MD |
PloS one |
| Common genetic variants associate with serum phosphorus concentration. |
Kestenbaum B
Fox CS |
Journal of the American Society of Nephrology : JASN |
| Polymorphisms in the NOS1AP gene modulate QT interval duration and risk of arrhythmias in the long QT syndrome. |
Tomás M
Priori SG |
Journal of the American College of Cardiology |
| Polymorphisms in the mitochondrial DNA control region and frailty in older adults. |
Moore AZ
Arking DE |
PloS one |
| New loci associated with kidney function and chronic kidney disease. |
Köttgen A
Fox CS |
Nature genetics |
| Genome-wide association study identifies GPC5 as a novel genetic locus protective against sudden cardiac arrest. |
Arking DE
Chugh SS |
PloS one |
| NOS1AP variant associated with incidence of type 2 diabetes in calcium channel blocker users in the Atherosclerosis Risk in Communities (ARIC) study. |
Chu AY
Kao WH |
Diabetologia |
| Common variants in KCNN3 are associated with lone atrial fibrillation. |
Ellinor PT
Kääb S |
Nature genetics |
| Genome-wide association study of PR interval. |
Pfeufer A
Heckbert SR |
Nature genetics |
| A genome-wide association analysis of serum iron concentrations. |
Tanaka T
Ferrucci L |
Blood |
| Transcobalamin-II variants, decreased vitamin B12 availability and increased risk of frailty. |
Matteini AM
Fallin MD |
The journal of nutrition, health & aging |
2009 |
| Title |
Authors |
Journal |
| A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells. |
Kent OA
Mendell JT |
Cancer biology & therapy |
| A genome-wide linkage and association scan reveals novel loci for autism. |
Weiss LA
Chakravarti A |
Nature |
| Understanding cardiovascular disease through the lens of genome-wide association studies. |
Arking DE
Chakravarti A |
Trends in genetics : TIG |
| Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization. |
Milan DJ
MacRae CA |
Circulation |
| Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. |
Benjamin EJ
Witteman JC |
Nature genetics |
| Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies. |
Nolte IM
Jamshidi Y |
PloS one |
| Multiple loci associated with indices of renal function and chronic kidney disease. |
Köttgen A
Fox CS |
Nature genetics |
| Genome-wide association study of blood pressure and hypertension. |
Levy D
van Duijn CM |
Nature genetics |
| Genomewide association studies: history, rationale, and prospects for psychiatric disorders. |
Cichon S
Sullivan PF |
The American journal of psychiatry |
| Common variants at ten loci modulate the QT interval duration in the QTSCD Study. |
Pfeufer A
Chakravarti A |
Nature genetics |
| Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations. |
Kao WH
Chakravarti A |
Circulation |
| Hybrids of aneuploid human cancer cells permit complementation of simple and complex cancer defects. |
Dezentje DA
Kern SE |
Cancer biology & therapy |
| Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are associated with increased risk of age-related macular degeneration. |
SanGiovanni JP
Chakravarti A |
PloS one |
| Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population. |
Arking DE
Chakravarti A |
PloS one |
2008 |
| Title |
Authors |
Journal |
| Molecular genetic and biochemical analyses of FGF23 mutations in familial tumoral calcinosis. |
Garringer HJ
White KE |
American journal of physiology. Endocrinology and metabolism |
| Differences in mtDNA haplogroup distribution among 3 Jewish populations alter susceptibility to T2DM complications. |
Feder J
Mishmar D |
BMC genomics |
| Validation and extension of an empirical Bayes method for SNP calling on Affymetrix microarrays. |
Lin S
Irizarry RA |
Genome biology |
| Association between microdeletion and microduplication at 16p11.2 and autism. |
Weiss LA
Daly MJ |
The New England journal of medicine |
| A common genetic variant in the neurexin superfamily member CNTNAP2 increases familial risk of autism. |
Arking DE
Chakravarti A |
American journal of human genetics |
| Widespread microRNA repression by Myc contributes to tumorigenesis. |
Chang TC
Mendell JT |
Nature genetics |
2007 |
| Title |
Authors |
Journal |
| Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. |
Chang TC
Mendell JT |
Molecular cell |
| Associations between genetic variants in the NOS1AP (CAPON) gene and cardiac repolarization in the old order Amish. |
Post W
Shuldiner AR |
Human heredity |
2006 |
| Title |
Authors |
Journal |
| Relative contribution of genetic and nongenetic modifiers to intestinal obstruction in cystic fibrosis. |
Blackman SM
Cutting GR |
Gastroenterology |
| Human embryonic stem cells have a unique epigenetic signature. |
Bibikova M
Fan JB |
Genome research |
| Identifying allelic loss and homozygous deletions in pancreatic cancer without matched normals using high-density single-nucleotide polymorphism arrays. |
Calhoun ES
Kern SE |
Cancer research |
| From vulnerable plaque to vulnerable patient--Part III: Executive summary of the Screening for Heart Attack Prevention and Education (SHAPE) Task Force report. |
Naghavi M
Shah PK |
The American journal of cardiology |
| A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. |
Arking DE
Chakravarti A |
Nature genetics |
| Variation in the ciliary neurotrophic factor gene and muscle strength in older Caucasian women. |
Arking DE
Walston J |
Journal of the American Geriatrics Society |
2005 |
| Title |
Authors |
Journal |
| Genomic alterations in cultured human embryonic stem cells. |
Maitra A
Chakravarti A |
Nature genetics |
| IL-6 gene variation is not associated with increased serum levels of IL-6, muscle, weakness, or frailty in older women. |
Walston J
Chakravarti A |
Experimental gerontology |
| Association between a functional variant of the KLOTHO gene and high-density lipoprotein cholesterol, blood pressure, stroke, and longevity. |
Arking DE
Dietz HC |
Circulation research |
2004 |
| Title |
Authors |
Journal |
| Genomics in sudden cardiac death. |
Arking DE
Spooner PM |
Circulation research |
2003 |
| Title |
Authors |
Journal |
| KLOTHO allele status and the risk of early-onset occult coronary artery disease. |
Arking DE
Dietz HC |
American journal of human genetics |
| Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome. |
Neptune ER
Dietz HC |
Nature genetics |
2002 |
| Title |
Authors |
Journal |
| Neisseria gonorrhoeae strain PID2 simultaneously expresses six chemically related lipooligosaccharide structures. |
Tong Y
Stein DC |
Glycobiology |
| Association of human aging with a functional variant of klotho. |
Arking DE
Dietz HC |
Proceedings of the National Academy of Sciences of the United States of America |
2001 |
| Title |
Authors |
Journal |
| Analysis of lipooligosaccharide biosynthesis in the Neisseriaceae. |
Arking D
Stein DC |
Journal of bacteriology |
1995 |
| Title |
Authors |
Journal |
| Genetic basis of Neisseria gonorrhoeae lipooligosaccharide antigenic variation. |
Danaher RJ
Stein DC |
Journal of bacteriology |
